Congratulations to Saan, who published an article in Bioorganic & Medicinal Chemistry Letters about the latest prospects of protease inhibitors as antiviral agents to combat infections with the Zika virus.
Biocompatible Peptide Macrocyclisation Generates Stable Protease Inhibitors
Check out our latest research article published in Organic Letters about a novel strategy to spontaneously cyclise peptides under physiological conditions. A substrate peptide of the Zika virus protease cyclised in this way produced an inhibitor of remarkable affinity and stability.
Proteases from dengue, West Nile and Zika viruses as drug targets
Check out our latest review about the potential of protease inhibitors to combat diseases associated with dengue, West Nile and Zika virus infections published in Biophysical Reviews.
Featured Letter in ACS Medicinal Chemistry Letters
Our latest paper on macrocyclic peptide inhibitors of the Zika virus protease has been published as a Featured Letter in ACS Medicinal Chemistry Letters and invited to contribute the cover for the February issue.
