Check out our latest research article published in Organic Letters about a novel strategy to spontaneously cyclise peptides under physiological conditions. A substrate peptide of the Zika virus protease cyclised in this way produced an inhibitor of remarkable affinity and stability.

Check out our latest review about the potential of protease inhibitors to combat diseases associated with dengue, West Nile and Zika virus infections published in Biophysical Reviews.

Our latest paper on macrocyclic peptide inhibitors of the Zika virus protease has been published as a Featured Letter in ACS Medicinal Chemistry Letters and invited to contribute the cover for the February issue.