Josemon completed his PhD in synthetic organic chemistry at ANU in 2019. He is working on new synthetic strategies to generate highly constrained bicyclic peptides that act as structurally pre-organised protease inhibitors. Josemon is also exploring new chemical strategies for protein bioconjugation.
Higher degree research students
Richard graduated with a BPharmSci(Hons) from Monash University and joined the group in 2019. He is working on antiviral agents to combat infectious diseases caused by alpha-, flavi- and coronaviruses. Richard is also exploring new chemical strategies for peptide macrocyclisation, which can be used directly inhibitor screening campaigns.
Sven graduated in pharmacy from Heidelberg University, Germany and joined our group in 2019. He is working on methods to form bicyclic peptides from macrocyclic precursors under biocompatible conditions. He is also investigated inhibitors of the SARS-CoV-2 main protease.
Barbara was a visiting PhD student from the Free University of Berlin, Germany. She worked on new strategies for protein-templated fragment ligation chemistry to develop new compounds that target Zika virus infections and bacterial drug resistance.
Saan graduated in pharmacy from the Free University of Berlin, Germany and joined our group in 2019. He developed switchable macrocyclisation conditions for peptide screening campaigns. Saan also studied inhibitors of the Zika virus protease, which resulted in a publication.
Xiaobai joined our lab for a CHEM3060 research project in 2020. He developed new, highly active inhibitors of the E. coli dephospho-coenzyme A kinase, as a new class of potential antibiotics.
Nuren Tasneem Natasha
Nuren was a Summer Scholar from Sydney University, working on new ways to conjugate proteins with tags for paramagnetic NMR spectroscopy.
Dylan is a PhB student at ANU who joined our lab for an advanced studies course in 2019, studying synthetic routes towards unnatural amino acids that allow the generation of highly constrained bicyclic peptides.
Tim was a visiting pharmacy student from Heidelberg University, Germany who joined our lab in 2019. He characterised the interactions of cyclic peptide inhibitors and small molecules with the protease from Zika virus. Tim’s work resulted in a publication.