Christoph

Christoph NitscheChristoph grew up in Anklam, Germany. He studied chemistry at the University of Halle-Wittenberg (Germany) and business administration at the Universities of Wales (UK) and Hagen (Germany). He had worked in the field of bioorganic chemistry at the Leibniz Institute of Plant Biochemistry and the University of Halle-Wittenberg before he relocated to Heidelberg University in 2010, where he began his PhD with Prof. Christian Klein. During his graduate work, he developed inhibitors of the dengue virus protease that exhibited antiviral activity in infected human cells.

After an internship at the Australian National University (ANU), Christoph held a position at Heidelberg University, where he invented covalent inhibitors that helped to solve the first crystal structure of the Zika virus protease. In 2015, he returned to the ANU as a postdoctoral fellow in the biomolecular NMR laboratory of Prof. Gottfried Otting. He has since introduced various chemical tools that facilitate the deeper understanding of protein-drug interactions by NMR spectroscopy. In 2018, Christoph temporarily relocated to the Free University of Berlin to work with Prof. Jörg Rademann on protein-templated chemical ligation.

In 2019, Christoph commenced his independent research endeavours on medicinal chemistry and bioconjugation at the Research School of Chemistry at the ANU, operating at the interface between synthetic chemistry, biochemistry and biophysics.

Awards

  • Discovery Early Career Research Award, Australian Research Council (2019)
  • Rising Star fellowship, Free University of Berlin (2018-2019)
  • Feodor Lynen fellowship, Alexander von Humboldt Foundation (2015-2018)
  • PhD prize for medicinal chemistry, German Chemical Society (2015)
  • PhD research scholarship, Studienstiftung des deutschen Volkes (2011-2013)
  • Scholarship, Studienstiftung des deutschen Volkes (2008-2010)