Biocompatible Peptide Macrocyclisation Generates Stable Protease Inhibitors

Check out our latest research article published in Organic Letters about a novel strategy to spontaneously cyclise peptides under physiological conditions. A substrate peptide of the Zika virus protease cyclised in this way produced an inhibitor of remarkable affinity and stability.

Table of contents graphic.jpg

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s